Priority: normal · Status: published
Date: 2026-10-01 (Endocrine Connections, publication)
Source: Endocrine Connections — PubMed — https://pubmed.ncbi.nlm.nih.gov/42862936/
What happened?
A study published in Endocrine Connections used continuous glucose monitoring (CGM) sensors and found frequent, often symptom-free episodes of low blood sugar in adults with adrenal insufficiency.
What is this about? (short)
Cortisol is one of the hormones that help keep blood sugar stable. In adrenal insufficiency cortisol is replaced with medication, but fluctuations during the day may affect blood sugar.
A CGM is a device with a small sensor worn on the skin that tracks blood sugar around the clock.
Study summary
The study compared 27 adults with adrenal insufficiency with 54 controls. Participants wore a blinded CGM (readings not shown to them) for 14 days.
Patients spent more time below the target range than controls. All patients (100%) had at least one low-glucose episode, and these were often asymptomatic.
Differences varied by treatment regimen, medication and the cause of adrenal insufficiency.
Who is it for?
The study concerns adults with adrenal insufficiency on cortisol replacement therapy.
Access / country context
Access to CGM devices and reimbursement vary by country; CGM is not yet routine practice in adrenal insufficiency.
What it means for patients in Türkiye
If you have symptoms such as weakness, sweating or shaking, or think you are having low blood sugar, tell your endocrinologist.
According to the authors, CGM data may help clinicians plan treatment, but do not change any medicine or dose on your own based on sensor readings. Your doctor decides.
Warning: This is a news summary, not dose or treatment advice. Ask your endocrinologist.
Prepared by: Asistan · 2 Nov 2026. Source: Endocrine Connections article abstract (PubMed).
Medical disclaimer: Information on this site is prepared by a patient community for general awareness; for diagnosis, treatment or dose changes always consult your own doctor (endocrinologist). In an emergency call your local emergency number.